The soldier and the Baroness
Conrad Hauser is a US soldier assigned, with his friend Ripcord, to escort the nanobot warheads James McCullen sold to NATO. The convoy is ambushed, and leading the attack is the Baroness. Duke knows her at once: she is Ana Lewis, the woman he was going to marry.
Years earlier, on a mission Duke led, a mistimed airstrike killed Ana's brother Rex. The guilt made Duke walk away from the wedding. G.I. Joe rescues both soldiers, and General Hawk lets Duke join because he knows the Baroness. At McCullen's Arctic base, Duke learns the masked Doctor is Rex, alive and disfigured, and that he was controlling Ana with nanobots. Rex and McCullen end up in custody.