Alice

Alice wakes in a mansion with no idea who she is. A squad takes her to the Hive, and bit by bit she remembers she was Umbrella security. At the end she wakes in a hospital and walks out into a ruined Raccoon City.

In Raccoon City, Alice helps rescue Angela and fights Nemesis, whom she learns is Matt. She sacrifices herself for Angela and wakes in a lab with new powers.

Five years later, Alice drifts through the desert, uses telekinesis and guides a convoy to Alaska. She kills Isaacs, and a clone Alice survives the base's destruction. At the end she warns Wesker that she and her clones are coming for him.

In Tokyo, Wesker injects her with an antivirus that erases her powers. Alice becomes an ordinary survivor and looks for Arcadia. She finds Claire, Chris and a group in a Los Angeles prison.

Trapped in an underwater base, Alice sees versions of herself in simulations, including a suburban mother. She finds Becky and gets her powers back when Wesker takes her to the White House.

Alice learns she is a clone of Alicia Marcus, the founder's daughter. She releases the antivirus, survives, and receives Alicia's childhood memories from the Red Queen.

Alice was created for the films. Wikipedia notes that the first film had no characters from the games, and the familiar names only arrived from the second.